Ru(II)/Os(II)-based Carbonic Anhydrase Inhibitors as Photodynamic Therapy Photosensitizers for the Treatment of Hypoxic Tumours

Youchao Wang (1) , Pierre Mesdom (1) , Kallol Purkait (1) , Bruno Saubaméa (2) , Pierre Burckel (3) , Pilippe Arnoux (4) , Céline Frochot (4) , Kevin Cariou (1) , Thibaud Rossel (5) , Gilles Gasser (1)

1 iCLeHS - Institute of Chemistry for Life and Health Sciences
2 Faculté de Pharmacie de Paris
3 IPG Paris - Institut de Physique du Globe de Paris
4 LRGP - Laboratoire Réactions et Génie des Procédés
5 UNINE - Université de Neuchâtel = University of Neuchatel

Photodynamic therapy (PDT) is a medical technique for the treatment of cancer. It is based on the use of non-toxic molecules, called photosensitizers (PSs), that become toxic when irradiated with...

Domaines: Chimie

Youchao Wang, Pierre Mesdom, Kallol Purkait, Bruno Saubaméa, Pierre Burckel, et al.. Ru(II)/Os(II)-based Carbonic Anhydrase Inhibitors as Photodynamic Therapy Photosensitizers for the Treatment of Hypoxic Tumours. Chemical Science, 2023, ⟨10.1039/D3SC03932C⟩. ⟨hal-04235882⟩