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Poster De Conférence Année : 2012

High resolution X-ray diffraction, ab initio calculations and thermodynamic measurements to go insight the polymorphism of drugs. Application to paracetamol and piracetam

Résumé

Studying polymorphism of pharmaceutical compounds is a growing field of activity. This is due to the economic pressure of the pharmaceutical industry and the more important awareness of the polymorphism consequences on the medicament properties, in particular chemical and physical stability. We have developed a fundamental approach to study polymorphism, which combines high-resolution X-ray diffraction, thermodynamic experiments and ab-initio calculations
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Dates et versions

hal-02301107 , version 1 (23-09-2020)

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  • HAL Id : hal-02301107 , version 1

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Nouha El Hassan, Anne Spasojevic - de Biré, Jean-Michel Gillet, Nour-Eddine Ghermani, Philippe Espeau, et al.. High resolution X-ray diffraction, ab initio calculations and thermodynamic measurements to go insight the polymorphism of drugs. Application to paracetamol and piracetam. 6th annual meeting of the “Control and Prediction of the Organic Solid State” (CPOSS) project, Apr 2012, Londres, United Kingdom. ⟨hal-02301107⟩
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